Thursday, 11th September CD1-MR1 Workshop 2025

Additional Chair: Branch Moody

• The role of MAIT cells during Plasmodium liver-stage infection   - Sidonia BG Eckle

• Microbiota-derived MAIT cell ligands diffuse passively across the gut barrier and control gradual MAIT cell accumulation with age - Francois Legoux

• Unconventional functions of CD1d - Patricia Barral

• Innate IL-17 producers - Lydia Lynch
• Impact of Diet-Induced Dyslipidemia on Group 1 CD1-Restricted Lipid Antigen-Specific T Cells - Chyung-Ru Wang
• Lymph nodes harbor distinct MAIT cell populations with varying residency behaviors and locations - Victoria Remy

• SLAMF6 regulates invariant natural killer T cell lineage diversity - Motoko Y. Kimura
• Identification of a novel innate-like human double-negative T cell population distinct from iNKT and MAIT cells - Kazuya Masuda
• Lipids presentation in non-classical MHC-I molecules from marsupials - Tiing Jen Loh
• MAIT cells represent a major population of antibacterial tissue-resident memory T (T_RM) cells in the human gastrointestinal tract - Edwin Leeansyah
• CD1a contributes to early bacterial and stress sensing in the skin - Karmella Naidoo
• Bystander cytokine cues activate CD1b-restricted T cells in humans and non-human primates - Cassie Winter
• Circulating microbiota-derived 5-OP-RU may drive MAIT cell accumulation overtime - Lilou Germain
• Unraveling the Role of TAK1 in iNKT Cell Development, Proliferation, and Survival - Bobby Zuniga
• From accessibility to identity: Epigenetic regulation of murine MAIT cell thymic development - Anne-laure Le Gac
• Tissue-Specific Lipid Metabolism is a Shared Feature of Innate T Cell Subsets   - Claire McIntyre

• Single-cell analysis results of the patient's blood in the phase I clinical trial of allogeneic iPS cell-derived invariant NKT cell monotherapy - Takahiro Aoki
• Pooled in vivo CRISPR screen for MAIT cell memory after Live Bacteria Vaccination - Gabriel Ascui-Gac
• Metabolic profile of human iNKT cells supports antitumor function in nutrient-deprived tumor environments - Nikhila S Bharadwaj
• MAIT cells possess direct cytotoxic potential against liver cancer, but are rendered dysfunctional within the tumour microenvironment - Katrin Böttcher
• CD1c Transgenic Mice as a Preclinical Platform for Evaluating CD1c-Restricted T Cell Immunity and Therapeutic Safety - Michela Consonni
• CAR-iNKT cell adoptive immunotherapy for metastatic colon cancer   - Gloria Delfanti
• Lactobacillaceae as protective MAIT cell activators in the vagina? - Caroline EMK Dricot
• Development of nanobodies to isolate and manipulate MAIT cells in humans and mice - Nicholas A Gherardin
• Characterization of the regulatory landscape of IL-17-producing human MAIT cells - Katie Healy
• Cord-derived invariant Natural Killer T cells to improve the outcome of hematopoietic stem cell transplantation - Jin Im
• Competition between KIR3DL3 and TMIGD2 is a checkpoint mechanism for γδ and CD8⁺ T cells - Laura Leaton
• Investigating infection-associated T cell antigens presented by MR1 - Songyi Li
• Perturbation of Invariant Natural Killer T cells by the Clonal Hematopoiesis-related inflammatory environment - Francesca Luca
• Phenotyping of peripheral MAIT cells from an HIV and Aging cohort using a 35-color spectral flow cytometry panel reveals the phenotypic diversity and specific age-associated enrichment of the CD4+ compartment - Christina S McConney
• The Unconventional Nature of the Human T Cell Response to Streptococcus pyogenes - Christopher Menne
• Past the pore of no return: Utilisation of the necroptotic program by MAIT cells - Timothy Patton
• Metabolic fuel choices control mouse and human MAIT cell functions - Tom Riffelmacher
• CD1b-restricted cytotoxic T cells recognizing a mycobacterial lipid TMM are conserved across primates - Yuki Sakai
• MAIT cell activation in HIV-induced neuroinflammation - Emily M. Slaby
• Mucosal-Associated Invariant T cells: Potential Adoptive Cellular Immunotherapy - Ebony Smith
• Blockade of AhR signaling augments the efficacy of NKT cell-based immunotherapy - Mariko Takami
• Optimized Syngeneic Neuroblastoma Models to Advance Cell Therapies - Ying Wang
• Generation of allogeneic CAR-NKT cells from HSPCs using a clinically guided culture method for cancer immunotherapy - Lili Yang
• Spatially resolved single-cell profiling reveals MAIT cell roles in sterile lung injury - Xiawei Zhang

• Remembering Dr. Masaru Taniguchi – His Contributions to iNKT Cell Research - Shinichiro Motohashi

• Pathways to human MAIT cell activation - Paul Klenerman
• Probing T-cell Responses to Mycobacterial Lipids in the Non-Human Primate Model - Chetan Seshadri

• Mechanisms of follicular helper NKT cell-mediated augmentation of antibody production by a pneumococcal protein and glycolipid vaccine - Yuki Kinjo
• Lung Resident MR1T Cells Across the Spectrum of Mycobacterium tuberculosis Infection - Dylan Kain
• MAIT cells protect against systemic Aspergillus fumigatus infection - Huimeng Wang
• Tissue dependent specialization of human MAIT cells - Johan Sandberg