Oral Presentation CD1-MR1 Workshop 2025

Acetoacetate suppresses colon cancer via an MR1-MAIT axis (#5)

Slater L Clay 1 2 , Geniver El Tekle 1 2 , Diogo Fonseca-Pereira 1 2 , Edrees Rasheed 3 , Yern-Hyerk Shin 4 , Natasha Andreeva 1 2 , Sena Bae 1 2 , Monia Michaud 1 2 , Jonathan N Glickman 5 , Jon Clardy 4 , Matthew G Vander Heiden 3 , Wendy S Garrett 1 2 6 7 8
  1. Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA
  2. Harvard T. H. Chan Microbiome in Public Health Center, Boston, MA, USA
  3. Department of Biology, The David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA, USA
  4. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School and Blavatnik Institute, Boston, MA, USA
  5. Department of Pathology, Harvard Medical School, Boston, MA, USA
  6. Broad Institute of Harvard and MIT, Cambridge, MA, USA
  7. Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA
  8. Department of Molecular Metabolism, Harvard T. H. Chan School of Public Health, Boston, MA, USA
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